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Updated: May 1, 2020
Hydroxychloroquine (HCQ) and Zinc Adult Protocols or Suggested Regimens:
No symptoms but high risk over age 55 or with diabetes, hypertension, black American, native American, Indian American, blood type A, then lowest weekly/biweekly then triweekly dose
HCQ 200 mg One pill every week x2 then every other week x2 then every third week until the pandemic is over. *
Daily zinc (at least Zinc 11mg if not 30mg or more), vitamin C (at least 1,000-2,000mg), vitamin D3 (2,000IU or 5,000IU for diabetic patients) and/or if more convenient, a daily multi-vitamin with zinc.
Mild symptoms and or high risk with questionable symptoms:
HCQ 200mg: One today one tomorrow and once a week x2 then every other week x2 then every third week until the pandemic is over (tapered to every other and every third week until the pandemic is over). *
Daily zinc, vitamin c and d / daily multivitamin if possible, as above.
High risk likely exposed healthcare worker:
HCQ 200mg each day for Three days (one today one tomorrow and one day after) for the first week and then one pill weekly x2 then every other week x2 then every third week until the pandemic is over. *
Daily zinc, vita c and d / daily multivitamin if possible.
If Covid-19 test positive and symptomatic then larger doses of HCQ 200mg twice a day x 5 days with Z-pack may be needed:
1.Hydroxychloroquine 200mg twice a day for 5 days 2. Azithromycin 500mg once a day for 5 days 3. Zinc sulfate 220mg (50mg elemental Zinc) once a day for 5 days
Daily zinc vita c and d / daily multivitamin if possible. Consider obtaining EKG prior to starting Azithromycin in combination with HCQ
Consideration for treating with longer term hydroxychloroquine 200mg once every three weeks may be helpful.
Contacts Covid-19 positive people or low risk patients who desire added low risk protection:
Hydroxychloroquine 200mg once every 3 weeks, if symptoms start, add a dose of HCQ200mg and get tested and call your physician for daily for more frequent dosing advice. *
Daily zinc, vita c and d / daily multivitamin if possible.
*If you’re sicker and you know it take an extra pill that day and call your physician right away. (HCQ200mg may be needed if symptoms persist or worsen on a day you did not already take the medication previously) Consideration of additional antibiotics such as doxycycline, azithromycin, Levaquin or metronidazole aka flagyl if asthmatic or if pulmonary symptoms occur. Those who are overweight/obese must take hydroxychloroquine early and each day they have symptoms; there is a much higher likelihood of ending up needing Mechanical Ventilation.
· Mutations are postulated to occur which may cause even those who rode out the disease previously to get a different version and experience similar symptoms and severity of disease perhaps now with permanently damaged heart and/or damaged lungs.
· Riding the disease out without some protection, including but not limited to low dose hydroxychloroquine may make surviving the next mutation more difficult.
All of the above should be in consultation with your physician.
Improving the Efficacy of Chloroquine and Hydroxychloroquine Against SARS-CoV-2 May Require Zinc Additives – A Better Synergy for Future COVID-19 Clinical Trials https://www.infezmed.it/media/journal/Vol_28_2_2020_9.pdf
Hospital Protocols https://spectator.org/a-report-from-the-front/ early HCQ as option
Country Recommendations of Hydroxychloroquine:
Costa Rica: https://qcostarica.com/hydroxychloroquine-the-drug-costa-rica-uses-successfully-to-fight-covid-19/
Italy: https://www.trustnodes.com/2020/03/29/italy-finally-starts-mass-treatment-with-hydroxychloroquine
Turkey: https://www.middleeasteye.net/news/coronavirus-turkey-hydroxychloroquine-malaria-treatment-progress
Russian Health Ministry Recommendation for : Post contact prevention in individuals with a single contact with confirmed case of COVID-19 Hydroxychloroquine 1st day: 400 mg 2 times (morning, evening), then 400 mg once a week for 3 weeks; Page 110 Annex 10 Recommended COVID-19 Drug Prophylaxis Schemes Group Recommended scheme Healthy faces Recombinant interferon alpha. Drops or spray in each nasal passage 5 times a day, up to 1 month (single dose – 3000 ME, daily dose – 15000-18000 ME). Post-exposure prophylaxis in individuals in single contact with a confirmed COVID-19 case 1. Hydroxychloroquine Day 1: 400 mg 2 times (morning, evening), further 400 mg once a week for 3 weeks; 2. Meflokhin Days 1 and 2: 250 mg 2 times (morning, evening), Day 3: 250 mg per day, further 250 mg once a week for 3 weeks. COVID-19 prophylaxis for persons in the focus of infection 1. Hydroxychloroquine Day 1: 400 mg 2 times at 12 hour intervals, further 400 mg once a week for 8 weeks; 2. Meflokhin Days 1 and 2: 250 mg 2 times at 12 h intervals, day 3: 250 mg per day, further 250 mg once a week for 8 weeks.
India: Hydroxychloroquine is firstline
Israel: